Kisspeptin PT-141 Nasal Stack

Kisspeptin PT-141 Nasal Stack from Direct Anti Peptide is a precisely formulated dual-peptide research tool combining Kisspeptin and PT-141 (Bremelanotide) in a nasal spray delivery system, manufactured to ≥98% purity for use in controlled laboratory and preclinical research settings. Designed for qualified researchers, this stack provides a convenient and reproducible method for studying two of the most scientifically relevant neuropeptides in reproductive endocrinology and neuroendocrine signalling. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Product Overview

The Kisspeptin PT-141 Nasal Stack is an advanced research formulation developed to support scientific investigation into the synergistic interactions between two well-characterised neuropeptides. Kisspeptin is a pivotal regulator of the hypothalamic-pituitary-gonadal (HPG) axis, while PT-141 (Bremelanotide) is a melanocortin receptor agonist with documented activity in neuroendocrine and behavioural research models. Together, these compounds represent a compelling area of inquiry for researchers studying reproductive function, hormonal signalling cascades, and arousal-related neurobiology. Direct Anti Peptide offers this stack in two size configurations to support both short-term pilot studies and extended research programmes.

Peptide Structure & Amino Acid Sequence

Kisspeptin is a RF-amide neuropeptide encoded by the KISS1 gene. The most studied bioactive fragment, Kisspeptin-10, comprises the C-terminal decapeptide sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂. It acts as an endogenous ligand for the KISS1R (GPR54) receptor and is a key upstream regulator of gonadotropin-releasing hormone (GnRH) secretion.

PT-141 (Bremelanotide) is a cyclic heptapeptide with the sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (CAS: 189691-06-3). It is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) and acts as a non-selective agonist at melanocortin receptors MC1R, MC3R, MC4R, and MC5R. Its activity at MC4R is of particular interest in neuroendocrine and behavioural research contexts.

Chemical & Physical Characteristics

• Formulation: Dual-peptide aqueous nasal spray solution
• Delivery Method: Intranasal (research administration)
• PT-141 CAS Number: 189691-06-3
• Appearance: Clear to slightly opalescent solution
• Solubility: Water-soluble; formulated in sterile aqueous vehicle
• Storage Stability: Stable under recommended refrigerated conditions
• Purity: ≥98% for each active peptide component

Purity & Analytical Verification (HPLC & MS)

Each batch of Kisspeptin PT-141 Nasal Stack produced for Direct Anti Peptide undergoes rigorous analytical testing prior to release. High-Performance Liquid Chromatography (HPLC) is used to confirm that both Kisspeptin and PT-141 meet the ≥98% purity threshold, while Mass Spectrometry (MS) verifies the molecular identity and integrity of each peptide component. These dual verification steps ensure that researchers receive a product of consistent, publication-grade quality suitable for reproducible preclinical experimentation.

Quality Control & Lyophilization Integrity

While this product is supplied in liquid nasal spray format rather than lyophilised powder, the same stringent quality control protocols apply. The aqueous formulation is prepared under controlled manufacturing conditions to prevent microbial contamination, peptide degradation, and concentration variance. Each production batch is assigned a unique lot number and is traceable through our internal QC documentation system, ensuring full accountability from manufacture through to fulfilment.

Safety, Handling & Laboratory Precautions

This product is strictly intended for use by trained research professionals in laboratory settings. Appropriate personal protective equipment (PPE), including gloves, eye protection, and a laboratory coat, should be worn when handling this formulation. Researchers should adhere to all applicable institutional biosafety protocols. This product must not be used on or administered to humans or animals under any circumstances. Keep out of reach of unauthorised personnel. In the event of accidental contact with skin or eyes, rinse thoroughly with water and consult your institution’s safety officer.

Reconstitution, Packaging & Storage

The Kisspeptin PT-141 Nasal Stack is supplied ready-to-use in nasal spray bottles and does not require reconstitution. Store the product at 2–8°C (refrigerated) and protect from direct light and heat. Do not freeze the liquid formulation. Once opened, use within the timeframe specified on the product label. Ensure the spray actuator is kept clean and capped between uses to maintain sterility and prevent evaporative concentration changes. Both size options are securely packaged to ensure safe transit and arrival in optimal condition.

Intended Research Use & Market Positioning

The Kisspeptin PT-141 Nasal Stack is specifically designed for researchers investigating reproductive endocrinology, neuroendocrine signalling, and HPG axis regulation. It is particularly relevant to studies examining the upstream control of GnRH pulsatility, melanocortin receptor pharmacology, and the potential synergistic interactions between KISS1R and MC4R signalling pathways. This stack is ideally positioned for use in behavioural neuroscience, preclinical pharmacology, and hormonal regulation research. Direct Anti Peptide is committed to providing researchers with best-price, high-purity peptide tools that support rigorous and reproducible science.

Ordering, Availability & Fulfillment

Buy Kisspeptin PT-141 Nasal Stack online today through Direct Anti Peptide and benefit from competitive pricing, secure checkout, and prompt dispatch. Both the 15ml and 30ml options are available for sale and ready to order now. Stock both sizes to maximise research flexibility — bulk orders attract additional savings. Our fulfilment team ensures careful, discreet packaging and reliable delivery to research institutions worldwide. For volume purchasing or institutional enquiries, contact our team directly for a tailored quote.

Legal & Regulatory Disclaimer

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. The Kisspeptin PT-141 Nasal Stack is sold exclusively for in vitro and preclinical research purposes by qualified scientific professionals. Direct Anti Peptide makes no claims regarding the therapeutic, diagnostic, or prophylactic suitability of this product. All purchasers are solely responsible for ensuring compliance with applicable local, national, and international laws and regulations governing the purchase, handling, and use of research peptides. This product has not been evaluated or approved by any regulatory authority for use in humans or animals.